Credit: Proceedings of the National Academy of Sciences (2025). DOI: 10.1073/pnas.2418624122 Scientists have uncovered new details about cellular filaments that play a critical role in wound healing, ...
This study presents a valuable finding regarding the role of Arp2/3 and the actin nucleators N-WASP and WAVE complexes in ...
Researchers have visualized at the molecular level how formins bind to the ends of actin filaments. This allowed them to uncover how formins mediate the addition of new actin molecules to a growing ...
An electron microscopy study revealed key details of actin filaments, which are essential structural elements of cells and muscles. Actin filaments -- protein structures critical to living movement ...
You’ve been wounded; nothing serious thankfully, but you watch your scrape go through the stereotypical stages of healing: first it’s raw, perhaps a bit bloody, but then the wound begins to close and ...
Model showing the release of phosphate in different parts of the actin filament. Actin in the core of the filament has a closed door while the back door at the end of the filament is open. A mutation ...
Actin filaments - protein structures critical to living movement from single cells to animals - have long been known to have polarity associated with their physical characteristics, with growing ...
Research has demonstrated that actin waves propagate via actin polymerization on the substrate-attached cell membrane at the wave’s front and disassembly at the back of the wave. 4 Proteins named Arp2 ...