Investigating chromatin's 3D architecture reveals its influence on gene regulation, shedding light on mechanisms underlying ...

This makes it far easier to perform this type of assembly in real life, because you’d need to generate a much smaller set of custom DNA molecules. These would then be mixed together and, voila, you’d ...

DNA can fold into complex shapes to execute new functions. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2023 / 06 / 230621164736.htm ...

SMC (structural maintenance of chromosomes) protein complexes are ring-shaped molecular motors essential for genome folding. Despite recent progress, the detailed molecu ...

To determine the structure of this BRCA2 complex, the researchers used X-ray crystallography. In this process, the protein crystal is bombarded with X-rays and the patterns that are generated when ...

Structure of a meiosis-specific complex central to BRCA2 localization at recombination sites. Nature Structural & Molecular Biology , 2021; 28 (8): 671 DOI: 10.1038/s41594-021-00635-0 Cite This Page : ...

More information: F. Li et al, Structural and molecular basis of PCNA-activated FAN1 nuclease function in DNA repair, Nature Communications (2025). DOI: 10.1038/s41467-025-59323-y Provided by ...

Chances are you've seen an illustration of DNA's double-helix structure and even pictures of the chromosomes that make up the human genome. But where and how does the famous double helix fit into ...

In nature, DNA contains the instructions for the cells that allow life to grow, thrive, and reproduce. Researchers see great potential in DNA for its ability to direct assemble of a wide range of ...

They knew DNA as one of the most complex of the “giant molecules” known to man. It was believed to have a long, chainlike structure consisting of repeating groups of atoms, with side groups ...