Do they have any relation with binding affinity? How do we search for new instances of a motif in this sea of DNA? Sequence motifs are short, recurring patterns in DNA that are presumed to have a ...
The results depicted in Figure 1 also consider the role of zinc (Zn) in Sp1-DNA binding. Sp1 is a protein that has multiple zinc-finger motifs, or regions known to bind to zinc; however ...
Within the NTase domain is an adenylate binding pocket composed of the six peptide motifs (I, Ia, III, IIIa, IV, and V) that define the covalent nucleotidyltransferase enzyme superfamily that includes ...
They explored combinations of various polymerases and DNA binding domains, focusing on structural motifs from nature. They were particularly drawn to features of T7 DNA polymerase—derived from the T7 ...
The model identified key transcription factor binding motifs—short DNA sequences critical for CRE activity—providing insight into how specific factors influence gene expression in different ...