Grey's Anatomy introduced fans to the iconic Meredith Grey, but it also introduced them to the swoon-worthy Derek Shepherd. The pair were presented as the show's most desirable couple, making them one ...

When Grey's Anatomy took off as a cultural phenomenon in the mid-2000s, Patrick Dempsey's Dr. Derek Shepherd also swiftly became one of the biggest heartthrobs on television. Nicknamed "McDreamy ...