A dose-response curve is the graphical representation of a dose-response relationship, the magnitude of response of an organism from exposure to drugs and chemical interactors.

Even stranger, the dose response curve for endocrine disruptors may be “non-monotonic” — that is, not show a consistent relationship between increasing dose and increasing effect.

In the case of hormesis investigators, that meant inverting the hormetic dip in the low-dose region of the standard dose-response curve (Figure 6), and labeling the beneficial effect (which is now ...

Analysis of dose-response curves for anti–HIV-1 drugs gave a noteworthy result. Each drug class had a characteristic slope ( Fig. 1d and Supplementary Table 1 ).

Small molecule drug discovery relies on the evaluation of one compound against another compound. Measurement of the activity of the small molecule against a target must be standardized by determining ...

Large-scale cell line profiling of drugs provides dose-response curves that contain numerous lesser-considered parameters. Understanding the reasons for systematic variation in these parameters ...

Secondary adrenal insufficiency was linked to changes to the cortisol secretion rate and adrenocorticotropic hormone, or ACTH, dose-response curve, according to findings published in Journal of ...

The investigators estimated dose-response curves for each antipsychotic drug compared with placebo separately and as a group. They did not have enough data for most of the single antipsychotics, ...

Pearl Therapeutics Completes Phase 2b Study of Glycopyrrolate, Defines Dose-Response Curve and Identifies Optimal Dose of PT001 September 13, 2012 REDWOOD CITY, Calif., Sept. 13, 2012 /PRNewswire ...