Gastric and esophageal cancers rank among the deadliest cancers Worldwide, due to their biological complexity, late diagnosis, and limited response to ...

Tiny extracellular vesicles known as exosomes are emerging as key regulators of the tumor microenvironment (TME), influencing how cancer progresses, spreads, and responds to treatment. In a new review ...

Exosomes, small vesicles released by cells, play a key role in intercellular communication within the TME. lncRNAs encapsulated in exosomes can be transferred between tumor and stromal cells, ...

Exosomes participate in drug resistance, vascular remodeling, and antigen presentation. Exosomes not only impair the function of immune cells but also reshape the tumor microenvironment, thereby ...

PlP-driven exosomal breakthroughs: Advancing immune solutions for complex tumor microenvironments. A phase 2 study of the OX40 agonist BGB-A445, in combination with docetaxel or BGB-15025, an HPK1 ...

Tiny extracellular vesicles known as exosomes are emerging as key regulators of the tumor microenvironment (TME), influencing how cancer progresses, spreads, and responds to treatment. In a new review ...

Head and neck cancer (HNC) remains a significant global healthcare challenge, characterized by persistently high incidence and mortality rates. Despite ...

Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment ...

The tumor microenvironment (TME) consists of mediators surrounding a tumor, including diverse cell types, blood vessels, and other cellular components. Certain elements of the TME can benefit patients ...

The inflammatory tumor microenvironment (TME) is a complex network of cancer, immune, and stromal cells interacting through cytokines and growth factors to drive tumor growth, angiogenesis, and immune ...