A prospective comparison of ER, PR, Ki67 and gene expression in paired sequential core biopsies of primary, untreated breast cancer. This is an ASCO Meeting Abstract from the 2015 ASCO Annual Meeting ...
Researchers at the University of California San Diego (UCSD) have demonstrated an intriguing new variation on the CRISPR gene-editing system, which involves fixing a mutation on one chromosome by ...
In mantle cell lymphoma (MCL), an aggressive form of B-cell non-Hodgkin lymphoma, TP53 mutations are known to affect patients’ prognosis—but questions remain. What does the heterogeneity of TP53 ...
A study led by Aaron Hobbs, Ph.D., and Rachel Burge, Ph.D., at MUSC Hollings Cancer Center, reveals why a specific gene ...
Researchers discover unexpected patterns in mutation risks across individuals, uncovering 13 distinct genomic patterns. The study provides crucial insights into cancer evolution, identifying the genes ...
Osaka, Japan – When creating a computer program, errors in the code can introduce bugs to the software. Similarly, errors in our body’s genetic code, DNA, which is stored in structures known as ...
Healthy cells work hard to maintain the integrity of our DNA, but occasionally, a chromosome can get separated from the others and break apart during cell division. The tiny fragments of DNA then get ...
Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...
An international study has identified more than 50 genes on the X chromosome in which mutations may cause poor sperm production. Nearly half of all men with low or zero sperm count have no medical ...
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