Applied Therapeutics will present new data from the INSPIRE trial for govorestat at the PNS Annual Meeting in May 2025. Applied Therapeutics, Inc. announced that it will present the full 12-month ...
Applied Therapeutics, Inc. announced promising 18 and 24-month results from the INSPIRE Phase 2/3 trial of govorestat, a treatment for Charcot-Marie-Tooth Sorbitol Dehydrogenase Deficiency (CMT-SORD).
Improvements in outcomes and reduction in sorbitol maintained through 24 months Statistically significant correlation between absolute reduction in sorbitol and change in 10MWRT and CMT-FOM Lower Limb ...
Interim primary endpoint met; Statistically significant correlation of sorbitol with the CMT-FOM clinical outcome composite (p=0.05) Sustained, statistically significant reduction in sorbitol in ...
The ongoing Phase 3 INSPIRE trial is evaluating the effect of AT-007 vs. placebo in patients with SORD Deficiency on sorbitol reduction as well as clinical outcomes in approximately 50 patients age 16 ...
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