Cell free DNA screening vs direct invasive procedures for detection of trisomy 21. For women with pregnancies at high risk for trisomy 21, performing cell-free DNA tests over direct invasive ...

Multicolor karyotyping procedures, such as multiplex fluorescence in situ hybridization (M-FISH), spectral karyotyping, or color-changing karyotyping, can be used to detect chromosomal rearrangements ...

No consensus exists whether women at increased risk for trisomy 21, 13, and 18 should be offered stand-alone rapid aneuploidy detection (RAD) or karyotyping. In this paper, the ethical implications of ...

Genetic abnormalities have been associated with 6 to 13% of stillbirths, but the true prevalence may be higher. Unlike karyotype analysis, microarray analysis does not require live cells, and it ...

A new test may be better at detecting potentially harmful genetic changes in children before they are born than current methods, researchers say. The test, called a chromosomal microarray, detected ...

Every expectant parent hopes and prays for a healthy baby. Careful consideration is given towards the well being of the baby by the mother-to-be for the entire duration of 9 months. But there are ...

When looking for genetic causes of a miscarriage, parental karyotyping might provide a clue even when the foetal tissue appears normal, researchers say. Their suggestion is based on a single case, ...