The sports supplement creatine may not be effective in building muscle, according to a new study from the University of New South Wales. Researchers and exercise scientists speak about the findings.

Are there additional risks of toxicity (or more acute development of toxicity) associated with aggressive loading doses? Are differences in efficacy and/or toxicity due to differing generic products?

Not everyone experiences water retention when taking creatine, but some people may gain a small amount of water weight, especially when using a loading dose of creatine. A loading dose of creatine ...

Creatine loading involves taking 20 to 25 g of creatine, split into 4 to 5 equal doses for 5 to 7 days. Following loading, 3 to 5 g per day is necessary to maintain your muscle stores of creatine.

For oral and IV: ≥17yrs: Monotherapy (partial-onset seizures): initially 100mg twice daily (alternatively, may initiate with a 200mg single loading dose, followed 12hrs later by 100mg twice ...

which involves four loading doses. According to a head-to-head trial called DEVOTE, which underpins the applications, the high-dose slowed neurodegeneration faster at day 64 than the current ...