Causal mediation analysis comprises a set of statistical techniques designed to disentangle the pathways through which an exposure or treatment exerts its effect on an outcome. By partitioning the ...

Over the past few months more healthcare articles have featured a new (at least for me) statistical methodology: mediation analysis. It doesn’t prove causality, but it can assign a value to the impact ...

(A) Represents mediation model 1: subjective cognitive complaints as the dependent variable (Y), the average MD as the independent variable (X), and the average cortical thickness as the mediator (M); ...

This course aims to provide an understanding of the statistical principles behind, and the practical application of, mediation analyses in epidemiology. Please click on the sections below for more ...