This study investigates the role of a key interaction between Tropomyosin (Tpm) and Troponin T (TnT) in the regulation of cardiac muscle contraction, with a particular focus on understanding ...

The study of molecular mechanics and cellular motility. Cell motility, regulation of cell shape and the mechanism and regulation of muscle contraction. Our lab’s main interest is the study of ...

In several disorders that involve muscle dysfunction — such as amyotrophic lateral sclerosis, spinal muscular atrophy and myasthenia gravis — muscle weakness results from limited neuronal input into ...

Osaka, Japan - Researchers at Osaka University used electron cryomicroscopy (CryoEM) to image essential cardiac muscle components, known as thin filaments, with unprecedented resolution. They also ...

The diagnosis of acute myocardial infarction (MI) has always required -- in addition to history of chest pain and abnormal ECG changes -- laboratory evidence of myocardial damage. The traditional ...

Troponin refers to three different proteins that help regulate the contractions of the heart and skeletal muscles. Normal troponin levels range from 0 to 0.04 nanograms per milliliter (ng/ml). The ...