DNA synthesis by single polymerase molecules ... the detection volume of the zero-mode waveguide. Formation of a phosphodiester bond releases the fluorophore, which quickly diffuses away, reducing ...
Adjacent ribose nucleotide bases are chemically attached to one another in a chain via chemical bonds called phosphodiester bonds. Unlike DNA ... the critical protein synthesis machinery in ...
TComparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases (Image: Wikimedia Commons, CC SA 3.0) The nucleotides are connected through phosphodiester bonds ...