Transposons, also known as jumping genes or mobile genetic elements as they can replicate and reinsert themselves in the ...

The study, published in Cell today, reveals how the retrotransposon copia completes its replication cycle and travels into the nucleus through the nuclear pores. The study is a collaboration between ...

Modern mammalian genomes, for example, are riddled with the scars of these copy-and-paste events, with retrotransposon-derived DNA now accounting for nearly 50 percent of the human genome. The most ...

Inflammasomes are huge, multi-protein complexes inside cells that spark inflammation when they sense danger. Inflammasomes can also sound the alarm when no pathogens are present, contributing to ...

We propose that silencing of retrotransposons occurs by cosuppression during early embryogenesis, but that this process is imperfect and produces a mosaic pattern of retrotransposon expression in ...

Following translation, reverse transcriptase converts the retrotransposon RNA into double-stranded DNA. This DNA copy of the retrotransposon then integrates, at a new location, into the genome of ...

We have carried out pioneering work on the development and application of retrotransposon markers in barley, in an EU project with the major European groups who are developing them for other crops.

For the first time, scientists have visualized a retrotransposon, a “jumping gene”, inside the cell of a complex organism. Advanced cryo-Electron Tomography allowed this feat at sub-nanometer ...