Amid a 5-6 start for the 49ers this season, head coach Kyle Shanahan sent a message to the locker room about being too online ...

The 49ers have revealed their latest injury report from Wednesday’s practice before their Sunday Night Football tilt against ...

With only a few weeks left on the college football slate, NFL draft season is beginning to hit its stride. Before the San ...

What to expect from Sunday Night Football's 49ers vs. Bills matchup. This is one of those games that feels like Buffalo's to ...

Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...

San Francisco 49ers running back Christian McCaffrey is three games into his return from injury. The two-time first-team ...

There is a High Risk of Weather Impact (ROWI) for the NFL's Sunday Night Football matchup between the San Francisco 49ers ...

San Francisco 49ers star linebacker Fred Warner revealed that he has been playing through a broken bone in his ankle since ...

The Bills attempt to win seven in a row when they host the 49ers in this Week 13 NFL odds, prediction, and pick.

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an ...

It’s Week 13 in the NFL, and the Buffalo Bills are preparing to host the San Francisco 49ers on Sunday Night Football at 8:20 ...

Bills' QB Josh Allen is the current favorite for MVP. Expectations aren't something I like to make a habit. However, it's ...