Researchers at UC Berkeley have built a microfluidic organ-on-a-chip system that compresses roughly 40 years of human aging ...

Now, in a study published March 30 in Cell Chemical Biology, UB scientists have shed light on one such stressor, showing that ...

Cellular senescence is a state characterized by permanent cell-cycle arrest, increased expression of markers such as p16^INK4a and p21^CIP1/WAF1, elevated DNA damage signals (e.g., γ-H2AX) and a ...

When cells experience enough chronic stress, they can stop dividing permanently. In this state of cellular limbo, known as ...

Study identifies impaired ER-to-golgi ceramide transport as a key regulatory node underlying senescence-associated sphingolipid remodeling.

There exists a complex synergistic relationship among cancer, circadian rhythms, and aging: aging is a major risk factor for cancer, disruption of circadian rhythms promotes tumor initiation and ...

Aging is a complex biological process characterized by the progressive decline of physiological integrity, leading to impaired function and increased vulnerability to disease. It is the strongest risk ...

There exists a complex synergistic relationship among cancer, circadian rhythms, and aging: aging is a major risk factor for cancer, disruption of circadian rhythms promotes tumor initiation and ...

When cells experience enough chronic stress, they can stop dividing permanently. In this state of cellular limbo, known as replicative senescence, cells remain alive but no longer proliferate.