Telomerase is a ribonucleoprotein enzyme that maintains the protective structures at the ends of eukaryotic chromosomes, called telomeres. In most human somatic cells, telomerase expression is ...

Study shows how telomerase can run amok, deleteriously capping damaged DNA, were it not for a first responder to DNA damage. The natural ends of chromosomes appear alarmingly like broken DNA, much as ...

The aging process - it's undignified, unwanted, and many would say unnecessary. After all, the cells in your body are constantly replacing themselves – why can't they do it without causing progressive ...

Research has recently uncovered a crucial step in the telomerase enzyme catalytic cycle. This catalytic cycle determines the ability of the human telomerase enzyme to synthesize DNA. Research from the ...

Premature aging can be reversed by reactivating an enzyme that protects the tips of chromosomes, a study in mice suggests. Mice engineered to lack the enzyme, called telomerase, become prematurely ...

Researchers at Arizona State University’s (ASU) School of Molecular Sciences and the Biodesign Institute’s Center for the Mechanism of Evolution have discovered an unprecedented pathway producing ...

Sometimes stories that start with pond scum can have good endings. In the case of the single-celled organism called Tetrahymena thermophila, important bits of DNA at the ends of its chromosomes led to ...

Role of Telomeres and Telomerase in the Pathogenesis of Human Cancer. If you have the appropriate software installed, you can download article citation data to the citation manager of your choice.

Telomeres – which are the DNA repeats that form the tips of chromosomes and are produced by the telomerase enzyme – play a crucial, and curious, role in the life of the cell. While chromosomes are ...

Some debate whether aging is in itself a disease. However, there is no doubt that by addressing it, one can prevent, delay, and even avoid age-related diseases such as cancer, pulmonary fibrosis, ...