Menkes disease (MD) is a recessive X-linked syndrome described by Menkes (1) more than 40 y ago. It is characterized by progressive cerebral and cerebellar degeneration, growth retardation, and ...

Translocation is a genetic abnormality in which part of a chromosome moves to another chromosome. Chromosomes are genetic structures within cells that hold genes. When translocation occurs, it causes ...

Translocations are chromosomal “cut and paste” errors that drive many lymphomas, a type of blood cancer and the sixth most common form of cancer overall. This includes mantle cell lymphoma, a rare but ...

IN 1960 Lejeune et al. 1 noted a centric fusion of 2 13–15 chromosomes in the cells of a person with Klinefelter's syndrome, and in 1962 Walker and Harris 2,3 reported several generations of a family ...

Robertsonian translocation is the most common form of chromosomal translocation in humans. It means that two chromosomes, the structures that make up a person’s DNA, join together in an abnormal way.

Changes in either chromosome structure or number can occur during cell division. Each human has 46 chromosomes, 22 pairs of autosomes and 1 pair of sex chromosomes (XX: female or XY: male). During ...

microRNA expression in circulating samples of pancreatic ductal adenocarcinoma patients: A search for circulating biomarkers. This is an ASCO Meeting Abstract from the 2014 ASCO Annual Meeting I. This ...

Most cases of Moebius syndrome are spontaneous, with no family history and no known genetic cause. In certain rare cases, the disorder has been associated with defects in chromosomes 3, 10, and 13.

Antagonists of growth hormone-releasing hormone potentiate radiation response in prostate cancer. Background: A small subset of human lung cancer harbors the fusion of the gene for echinoderm ...