C2H2 zinc finger proteins are the largest group of DNA-binding factors for transcription—the process of copying genetic ...

Shortly after this publication, Bogdanove struck up a collaboration with Daniel Voytas, a plant geneticist at the University ...

To meet this need, Indraneel Ghosh and David Segal at the University of Arizona put together their respective expertise in split protein assembly and zinc finger–DNA interactions. Split versions ...

as DNA recognition and cutting take place in one protein segment. Another result of this research are zinc finger nucleases. These artificial enzymes consist of a sub-unit that recognizes the desired ...

After testing the targeting capabilities of several different DNA binding domains, the team settled on a zinc finger protein—a little curlicue-shaped protein that performed the best in terms of ...