DNA-binding C2H2 zinc finger proteins also regulate RNA processing, researchers discover
C2H2 zinc finger proteins are the largest group of DNA-binding factors for transcription—the process of copying genetic ...
The Scientist5d
A Tale of How TALENs Launched the Genome Editing Revolution
Shortly after this publication, Bogdanove struck up a collaboration with Daniel Voytas, a plant geneticist at the University ...
Max Planck Society7y
From restriction enzymes to CRISPR-Cas9
as DNA recognition and cutting take place in one protein segment. Another result of this research are zinc finger nucleases. These artificial enzymes consist of a sub-unit that recognizes the desired ...
Nature10y
DNA makes GFP shine
To meet this need, Indraneel Ghosh and David Segal at the University of Arizona put together their respective expertise in split protein assembly and zinc finger–DNA interactions. Split versions ...
The Scientist11mon
An Epigenetic Strategy to Control Bad Cholesterol
After testing the targeting capabilities of several different DNA binding domains, the team settled on a zinc finger protein—a little curlicue-shaped protein that performed the best in terms of ...