Gut

Rectal lesion with a submucosal tumour-like appearance in a middle-aged woman

A 49-year-old woman had a rectal lesion detected during a screening colonoscopy and was referred to our institution for ...
Gut

Diagnostic endoscopic resection for assessing potential residual disease after neoadjuvant therapy for oesophageal adenocarcinoma

A subset of patients with oesophageal cancer shows a marked response to neoadjuvant chemoradiotherapy, yet post-treatment ...
Gut

Comment on: Therapeutic inhibition of HBsAg and HBV cccDNA through a novel phased combination treatment: glycine and interferon-α

We read with great interest the recent study by Lin Huang and colleagues, which demonstrates that glycine supplementation ...
Gut

Molecular and cellular consequences of tumour-autonomous IL-6 signalling in intrahepatic cholangiocarcinoma

Background High serum levels of interleukin 6 (IL-6) predict poor prognosis in intrahepatic cholangiocarcinoma (iCCA), a ...
gut.bmj

Pueraria lobata-derived exosome-like nanovesicles alleviate rheumatoid arthritis via targeting Ruminococcus gnavus phenylethylamine production

Background Gut microbiota has been widely recognised as playing a critical role in maintaining immune imbalance and the development of rheumatoid arthritis (RA). As key roles mediating interkingdom ...
gut.bmj

Increased expression of interleukin 17 in inflammatory bowel disease

Department of Internal Medicine, Shiga University of Medical Science, Seta-Tukinowa, Otsu 520-2192, Japan Correspondence to: Dr A Andoh, Department of Internal Medicine, Shiga University of Medical ...
gut.bmj

PGAM5-mediated programmed necrosis of hepatocytes drives acute liver injury

Objectives Autoimmune hepatitis (AIH) is a severe necroinflammatory liver disease associated with significant mortality. Although loss of hepatocytes is generally recognised as a key trigger of liver ...
gut.bmj

Sulphation and secretion of the predominant secretory human colonic mucin MUC2 in ulcerative colitis

a Pediatric Gastroenterology and Nutrition, Department of Pediatrics, University of Amsterdam, Academic Medical Centre, Amsterdam, The Netherlands, b Pediatric Gastroenterology and Nutrition, ...
gut.bmj

GASTRIC ANTRAL VASCULAR ECTASIA: CLINICAL FEATURES, ASSOCIATIONS AND PROGNOSIS

Introduction Gastric antral vascular ectasia (GAVE) is a rare disorder characterised by upper GI bleeding, chronic iron-deficiency anaemia and endoscopic findings of columns of red tortuous vessels ...
gut.bmj

Fukuoka criteria accurately predict risk for adverse outcomes during follow-up of pancreatic cysts presumed to be intraductal papillary mucinous neoplasms

Correspondence to Dr Suresh T Chari, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA; chari.suresh{at}mayo.edu Objective Fukuoka ...
gut.bmj

Gut microbiota modulate T cell trafficking into human colorectal cancer

Objective Tumour-infiltrating lymphocytes (TILs) favour survival in human colorectal cancer (CRC). Chemotactic factors underlying their recruitment remain undefined. We investigated chemokines ...
gut.bmj

Inflamed and non-inflamed classes of HCC: a revised immunogenomic classification

Objective We previously reported a characterisation of the hepatocellular carcinoma (HCC) immune contexture and described an immune-specific class. We now aim to further delineate the immunogenomic ...