San Francisco has been up and down all season ... Check out expert picks and best bets for every NFL game this week. Buffalo had its bye and the 49ers are so banged up that it’s tough to back them in this spot — especially cause the Bills are hitting ...

The San Francisco 49ers are 5-6 entering their matchup with the Buffalo Bills on Sunday, and an NFL executive called out 49ers HC Kyle Shanahan for mishandling late-game situations. Colin Cowherd discusses this criticism and if it’s the biggest issue the 49ers have right now.

This is the fifth time the Bills are playing in prime-time this year and they are 3-1, though the loss did come in their only other SNF appearance, a 35-10 beatdown in Baltimore.

One NFL team executive believes the San Francisco 49ers' 5-6 record is partially a product of Kyle Shanahan's coaching. "It's a combination of injuries

It’s Week 13 in the NFL, and the Buffalo Bills are preparing to host the San Francisco 49ers on Sunday Night Football at 8:20 p.m. Buffalo (9-2) enters the contest having won six straight and is coming off a bye week. Meanwhile, San Francisco (5-6) has dropped two straight and three of five as injuries continue to pile up.

Who plays whom in NFL Week 13? Take a look at the 16 games on the Week 13 NFL schedule this week, starting with three games on Thanksgiving (Chicago Bears vs Detroit Lions, New York Giants vs Dallas Cowboys,

Bills' QB Josh Allen is the current favorite for MVP. Expectations aren't something I like to make a habit. However, it's hard not to expect the best from Allen and the Bills this week. Beating the Chiefs the way they did helped them check off that confidence box, and they did it on their 12th straight week of football.

Watching NFL games, including Fox broadcasts, is simple with Hulu + Live TV, which includes 90 channels, unlimited DVR storage and access to NFL preseason games, live regular season games and studio shows. The service includes ESPN+ and Disney+ in the subscription.

NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco 49ers and Buffalo Bills.

After the Green Bay Packers moved to 8-3, things are looking rosy as far as playoff qualification goes. Here's what to know.

The Dolphins defense has been a bright spot so far in 2024 and this offseason they are predicted to add a key piece from the NFC.