Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

San Francisco 49ers star Deebo Samuel debuted his new podcast Tuesday and was quickly met with a litany of bad reviews on X and YouTube.

The San Francisco 49ers have played games without Deebo Samuel Sr. in the last year and a half. And they’ve played games without Christian McCaffrey in the last year and a half. But they’ve never played a game in that span without either Samuel or McCaffrey,

San Francisco 49ers safety Talanoa Hufanga was a full participant in practice for the first time since tearing a ligament in his knee last November and could be set to return to game action this week.

Here are eight stats and facts to know for Week 3 at SoFi Stadium. It’s been a tough start to the year for the Rams defense. No team in the league has allowed more yards than the Rams, who have allowed an NFL-high 852 yards, 489 of which came on Sunday against the Cardinals.

With all the injury issues and slow starts surrounding the 49ers' offense, former Super Bowl-winning quarterback Steve Young has a recommendation for quarterback Brock Purdy—run the ball.

While there is no doubt that the San Francisco 49ers have Super Bowl aspirations, it will be led by star quarterback Brock Purdy who looks to redeem himself after last season. If there is one aspect about Purdy's game that has been improved and will lead to title success for the 49ers,

The San Francisco 49ers will need more from their roster in the coming weeks, with running back Christian McCaffrey and wide receiver Deebo Samuel sidelined.