A total of 1,680 adults and 41 adolescents were randomly assigned to brensocatib or placebo. The researchers found that the annualized rate of pulmonary exacerbations was 1.02, 1.04, and 1.29 in ...

Brensocatib reduces the annualized rate of pulmonary exacerbations in patients with bronchiectasis compared to placebo, with rate ratios of 0.79 and 0.81 for 10 mg and 25 mg doses, respectively.

Isaac Arthur The Geopolitics of Space Colonization Posted: April 24, 2025 | Last updated: April 24, 2025 A new Space Race has begun, and as governments and corporations begin seeking to develop ...

Brensocatib significantly reduced the rate of pulmonary exacerbations and slowed lung function decline in patients with non-cystic fibrosis bronchiectasis in the Phase III ASPEN trial. "Bronchiectasis ...

Largest Global Clinical Trial Ever Conducted in Bronchiectasis Demonstrates Statistically Significant and Clinically Meaningful Reduction in Frequency of Pulmonary Exacerbations Versus Placebo ...

In bronchiectasis, neutrophilic inflammation is associated with an increased risk of exacerbations and disease progression. Brensocatib, an oral, reversible inhibitor of dipeptidyl peptidase 1 ...

Neutrophils are the core airway inflammatory cell in bronchiectasis. The drug appeared safe, although with a somewhat higher incidence of hyperkeratosis. Targeting airway inflammation with ...

Brensocatib, an oral, reversible inhibitor of dipeptidyl peptidase 1, may lower the rate of pulmonary exacerbations in patients with bronchiectasis. New research findings are summarized in a short ...

Yes, you read that right. African countries actually have many advantages. Warm weather all year round, fertile soil, abundant natural resources. Nice, right? Well, it is precisely because it is ...

The pontiff was also affected by a "previous episode of acute respiratory failure in bilateral multimicrobial pneumonia, multiple bronchiectasis, arterial hypertension and type II diabetes." ...

multiple bronchiectasis, arterial hypertension and type II diabetes.” The Vatican also announced that, in keeping with the Pope’s will, Francis will be buried in a simple underground tomb in ...