CRISPR-Cas9 technique targeting epigenetics reverses disease in mice. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2017 / 12 / 171207141735.htm ...

A more efficient delivery of a CRISPR/Cas9 therapeutic to adult mice with the metabolic disease Tyrosinemia type I developed may also prove to be safer for use in humans. A study shows that the ...

The CRISPR-Cas9 gene editing system just became more convenient. The system’s Cas9 component, a nuisance to incorporate into animal models, is an intrinsic part of a newly developed mouse strain.

Mouse livers were engineered via a one-time genome editing to secrete a GLP-1, cutting weight gain and improving glucose ...

researchers have utilized CRISPR-Cas9 gene editing in mice with a form of Fragile X Syndrome to alter gene expression, resulting in reduction of repetitive behaviors. Fragile X Syndrome (FXS) is ...

But with Cas9 mice, researchers will only have to inject the guide RNA, which pilots the Cas9 to the target gene sequence, in order to alter virtually any part of the mouse genome. This will allow ...

PUMP IT UP A new type of CRISPR/Cas9-based gene therapy turned on muscle-building genes in mice that have muscular dystrophy.Muscle fibers (magenta) from mice that got the therapy (right) were ...

Applications of the CRISPR-Cas9 system to edit the genome have widely expanded to include DNA gene knock-out, deletions, chromosomal rearrangements, RNA editing and genome-wide screenings. Here we ...

In a world first, scientists have created mice with two fathers, capable of having offspring of their own. It’s a huge step forward for our understanding of mammalian reproduction, and could, in ...

Since wild mice don’t naturally make Cas9, the gene drive as it is currently designed wouldn’t be able to spread. CopyCat also works only in female mice.