Life depends on genes being switched on and off at exactly the right time. Even the simplest living organisms do this, but ...

Scientists at the Icahn School of Medicine at Mount Sinai have discovered a possible reason why some cases of melanoma—a ...

A new study reveals that distal gene regulation via DNA looping evolved 150 million years earlier than previously believed.

The study by Li et al. provides fundamental findings supported by convincing evidence that they defined cellular reprogramming of androgen receptor in neuroendocrine prostate cancer (NEPC). The ...

Approximately 15 million USD; Oryzon to validate epigenetic agents by applying a personalized medicine approach for rare and orphan diseases; Oryzon will explore Aggression in spe ...

PacBio was the first to detect native epigenetic modifications alongside accurate DNA sequencing. With the integration of the CUHK deep learning models, our technology will be able to detect many ...

and observed that among families with less accessible chromatin, ERVKs had the highest number of enriched TF motifs in adult SPGs (Table S5). Top hits included TFs with known regulatory functions in ...

Since 2014, she leads her own research team in Weill Cornell Medicine in New York studying the critical interplay between TFs, 3D chromatin organization and transcription during cell cycle or cell ...