Humans’ DNA-Binding Motifs Surprisingly Distinctive. May 28, 2019. The best-laid plans of fruit flies and scientists sometimes go awry.

A new DNA-binding motif that does not resemble any previously identified motifs has been defined by 16 different proteins, whose DNA-binding domain sequences are aligned in Fig. 1.

The bound DNA is then eluted, amplified, sequenced, and analyzed with a customized TF-motif discovery software. Using their method, the authors systematically characterized the DNA-binding motifs of ...

Remote-controlled microflow using light-controlled state transitions within DNA condensates has been reported by scientists ...

To confirm the presence of these i-motifs in human DNA and pinpoint their locations, the Sydney team created a special fragment of an antibody molecule capable of binding to the i-motif structure.

What you get here is a lot more than what you see at first glance. On the opening page of the rather vanilla DNA-Binding Motifs page is a set of links to structures for the four major protein ...

Later, the DNA unfolded back into its usual form, and the i-motifs disappeared. According to Dinger, this probably means the i-motifs play a very specific role in regulating the transcription process.

To be clear, not just any piece of DNA can fold itself into the i-motif shape. There must be a specific sequence of letters that include several cytosines, which are written as Cs in the genetic code.

Scientists have discovered a new DNA structure that is inside human cells and have dubbed the structure "i-motif." I-motif resembles a twisted knot of DNA rather than the double helix were all ...

Now, Australian scientists have found a new form, a twisted knot known as the i-motif, in living cells for the first time. ... This shape was identified in 1953 as DNA's most common form, ...