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From our DNA strands to fishing rods to art, knots are all around us. Ana Wright, a Davidson College assistant mathematics ...
This article makes a valuable contribution to the field by uncovering a molecular mechanism for miRNA intracellular retention, mediated by the interaction of PCBP2, SYNCRIP, and specific miRNA motifs.
Reactions involving the transfer of a phosphoryl (−PO32–) group are fundamental to cellular metabolism. These reactions are catalyzed by enzymes, often large and complex, belonging to the ...
To detect RBP-specific binding motifs, a generalized linear model (glm) assuming a binomial-distributed response (logistic regression) was used to predict motif presence as the dependent variable, ...
In a study of human immune cells infected with HIV, the virus that causes AIDS, scientists at Johns Hopkins Medicine say a ...
AlphaGenome scores mutation effects across coding and non-coding DNA, bringing gene insights to the base-pair level.
It follows a previous report showing that the Werner syndrome protein WRN and its interacting protein WRNIP1 are indispensable for translesion DNA synthesis (TLS) by Y-family DNA polymerases (Pols).
Remote-controlled microflow using light-controlled state transitions within DNA condensates has been reported by scientists ...
Remote-controlled microflow using light-controlled state transitions within DNA condensates has been reported by scientists from Institute of Science ...
AI is being used to model gene regulation and predict cellular behavior from transcriptomic data. Learn how these tools aid discovery in biology, medicine, and synthetic biology—along with key ethical ...
LINE-1, a "jumping gene" making up 20% of the genome, invades DNA during cell division using protein-RNA clusters, offering insights into genome evolution and disease. Viruses are masters of hijacking ...