A dose-response curve is the graphical representation of a dose-response relationship, the magnitude of response of an organism from exposure to drugs and chemical interactors.

Even stranger, the dose response curve for endocrine disruptors may be “non-monotonic” — that is, not show a consistent relationship between increasing dose and increasing effect.

In the case of hormesis investigators, that meant inverting the hormetic dip in the low-dose region of the standard dose-response curve (Figure 6), and labeling the beneficial effect (which is now ...

Small molecule drug discovery relies on the evaluation of one compound against another compound. Measurement of the activity of the small molecule against a target must be standardized by determining ...

Large-scale cell line profiling of drugs provides dose-response curves that contain numerous lesser-considered parameters. Understanding the reasons for systematic variation in these parameters ...

Analysis of dose-response curves for anti–HIV-1 drugs gave a noteworthy result. Each drug class had a characteristic slope ( Fig. 1d and Supplementary Table 1 ).

Secondary adrenal insufficiency was linked to changes to the cortisol secretion rate and adrenocorticotropic hormone, or ACTH, dose-response curve, according to findings published in Journal of ...

Stylized curves that illustrate the linear, threshold, and hormetic dose-response models for carcinogens. The central pillar upon which toxicological assessments are built is the dose-response ...

The investigators estimated dose-response curves for each antipsychotic drug compared with placebo separately and as a group. They did not have enough data for most of the single antipsychotics, ...