Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...
DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...
DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that ...
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Defective DNA protein repair triggers inflammation and premature aging
Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...
Cellular findings show Telomir-Zn modulates intracellular metal balance linked to oxidative stress, mitochondrial dysfunction ...
Among them was David Liu, a biochemist at the Broad Institute and Harvard University in Cambridge, Massachusetts. Liu isn’t a ...
In jellyfish and sea anemones, neurons accumulate DNA damage while animals are awake and repair that damage during sleep.
Scientists have reversed severe memory loss in two mouse models of Alzheimer’s by restoring the brain’s energy supply. Late-stage mice showed brain tissue repairing itself once fuel balance returned, ...
Akeega, an oral dual mechanism therapy pairing niraparib with abiraterone, has won a positive committee opinion in Europe for ...
A bacterium best known for causing gum disease may also influence how breast cancer begins and spreads. A team at the Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy r ...
Colorectal cancer has long baffled scientists because, unlike most tumors, patients often do better when their cancers are ...
Fusobacterium nucleatum can drive DNA damage, tumor growth and metastasis, with heightened effects in cells with BRCA1 gene mutations.
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