More information: Sofia Tseranidou et al, Nucleus pulposus cell network modelling in the intervertebral disc, npj Systems Biology and Applications (2025). DOI: 10.1038/s41540-024-00479-6 ...

Intervertebral disc disease (IVDD) occurs when discs bulge or burst, compressing the spinal cord. 1 Symptoms range from pain ...

Figure C shows how this position increases force on back side of intervertebral discs, which may cause it to bulge forwards. This could potentially lead to a herniated disc. Hips rotate backward ...

A collaborative team from the University of Macau and Nanjing University found, using clinical databases and samples, that the loss of a protein named MFG-E8 in nucleus pulposus (NP) tissue is a ...

Background Back pain and intervertbral disc (IVD) damage are common problems experienced by astronauts. We hypothesize this is from paraspinal muscle deconditioning, ∼5 cm body lengthening from spinal ...

A recent study has unveiled the pivotal role of Ferroptosis Suppressor Protein 1 (FSP1) in intervertebral disc degeneration (IDD), a primary cause of chronic lower back pain. Researchers ...

As the world's population ages, intervertebral disc degeneration (IDD) has become a major medical issue, causing chronic lower back pain and mobility ...

Objectives: To observe the prevalence of lumbar intervertebral disc degeneration in elite athletes as compared with published literature of changes seen in non-athletes—that is, normal population.