An international research team has deciphered a mechanism of the evolutionary arms race in human cells. The findings provide ...

Studies demonstrate that intestinal epithelial cells upregulate PD-L1 following stimulation with gut microbial metabolites (e.g., L-DNA), promoting activated Th2 cell apoptosis to modulate local ...

The study results broadened the genetic basis of CHH that considered retrotransposon insertions. Importantly, this case emphasizes the need for additional genomic analyses in patients with CHH who had ...

Endogenous retroviruses (ERVs), a type of retrotransposon, stem from ancient retroviral insertions into germline cells and can feature two long terminal repeats (LTRs) flanking their proviral genome ...

Current studies on PD-1/PD-L1 small-molecule inhibitors mainly focus on modifying the linker region between the biphenyl ring and amino acid side chains, or transforming the biphenyl ring into a ...