Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization ...

Two novel agents targeting angiopoietin-like protein 3 demonstrated safety and lipid-lowering capabilities in phase 2 trials, ...

Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level. The ...

Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue ...

A new fluid biomarker for Parkinson’s disease (PD) was developed, offering a high-accuracy biological classification, ...

A new tissue expansion method enables scientists to use mass spectrometry imaging to simultaneously detect hundreds of molecules at the single cell level in their native locations.

This study addresses the structural basis of voltage-activation of BK channels using atomistic simulations of several microseconds, to assess conformational changes that underlie both voltage-sensing ...

These vesicles consist of a spherical bilayer structure surrounding an aqueous ... Through the addition of agents to the lipid membrane, or the alteration of the surface chemistry, liposome ...

Department of Chemistry, Scripps Research, 10550 North Torrey Pines Road, La Jolla, California 92037, United States ...