If you're into fitness, you've probably heard of creatine. It's like that trusty gym buddy: popular, reliable, and always ...

The sports supplement creatine may not be effective in building muscle, according to a new study from the University of New ...

Are there additional risks of toxicity (or more acute development of toxicity) associated with aggressive loading doses? Are differences in efficacy and/or toxicity due to differing generic products?

Creatine loading involves taking 20 to 25 g of creatine, split into 4 to 5 equal doses for 5 to 7 days. Following loading, 3 to 5 g per day is necessary to maintain your muscle stores of creatine.

Barth and DeVincenzo [5] described a method by which 20 mg of vancomycin per kilogram was administered as a loading dose posthemodialysis, followed by 500 mg after each hemodialysis session.

Not everyone experiences water retention when taking creatine, but some people may gain a small amount of water weight, especially when using a loading dose of creatine. A loading dose of creatine ...

For oral and IV: ≥17yrs: Monotherapy (partial-onset seizures): initially 100mg twice daily (alternatively, may initiate with a 200mg single loading dose, followed 12hrs later by 100mg twice ...

which involves four loading doses. According to a head-to-head trial called DEVOTE, which underpins the applications, the high-dose slowed neurodegeneration faster at day 64 than the current ...