Patients with STEMI who underwent primary PCI had better clinical outcomes — and no greater risk for bleeding — with a 600-mg loading dose compared with 300 mg. Given that platelet inhibition ...

Are there additional risks of toxicity (or more acute development of toxicity) associated with aggressive loading doses? Are differences in efficacy and/or toxicity due to differing generic products?

Positive 3-year results from the phase III PHOTON study were presented at the recent American Academy of Ophthalmology (AAO) ...

Does timing of an atorvastatin loading dose make a difference in PCI for ACS? C. Michael Gibson and Renato Lopes discuss.

Individualized. Dose (units required)= [desired (% of normal) – baseline (% of normal) AT-III level] X weight (kg)/1.4. Loading dose: increase AT-III to 120% of normal. Subsequent dose should be ...

No clear trends were observed in safety or efficacy data to determine if a single loading dose or multiple loading doses of aldesleukin would lead to better outcomes, and clinical investigation is ...