The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The ...

Tom Brady drew headlines after he had a rocky debut to his NFL broadcasting career, but Thanksgiving could serve as a ...

Former Iowa Hawkeyes star George Kittle is in the midst of what has to be the most trying season of his NFL career. Kittle's ...

San Francisco 49ers’ Christian McCaffrey (23) scores the winning touchdown late in the fourth quarter against the Green Bay ...

Two Green Bay Packers starters, cornerback Jaire Alexander and linebacker Edgerrin Cooper, did not practice on Friday and ...

With veteran Brandon Allen set to start at quarterback, the Niners are optimistic that star left tackle Trent Williams will ...

Under head coach Kyle Shanahan, the San Francisco 49ers have spent years falling just inches short of the franchise’s sixth ...

No Brock Purdy or Nick Bosa, but the 49ers are optimistic Trent Williams can now play, he’ll be evaluated pre-game.

The 49ers have dealt with injuries to key players all season. Brandon Aiyuk injured his knee, Brock Purdy missed last week's ...

San Francisco 49ers offensive tackle Trent Williams was seen in the locker room on Wednesday using a scooter as he recovers ...

Wide receiver Chris Conley, linebacker Curtis Robinson and more San Francisco 49ers players shared what they're most grateful ...

Amid a wicked Super Bowl hangover and heading towards what is likely a losing season, it’s natural that head coach Kyle ...