The session emphasized different strategies to initiate buprenorphine, naltrexone, acamprosate, gabapentin, and phenobarbital ...

Weak partial agonists that promote a desensitized state of the α7 nicotinic acetylcholine receptor (nAChR) have been associated with anti-inflammatory effects. Exemplar compounds feature a tertiary or ...

Although opioid agonist treatment for opioid use disorder (OUD) is effective in reducing illicit opioid use, 1 this therapy is vastly underused in the treatment of OUD. 2 In the United States ...

The main findings of this study are that levormeloxifene, the levorotatory form of a partial estrogen receptor agonist, like estrogen, lowers plasma cholesterol and has a direct antiatherogenic effect ...

In drug discrimination testing using mice trained to discriminate between 3 mg/kg IBNtxA and vehicle, the κ-agonist U-50488 fully substituted for IBNtxA. MOR agonist morphine, δ-agonist SNC162, NOP ...

Why 7OH Deserves Independent Scientific Attention Pharmacological Profile Mechanism: Partial mu-opioid receptor agonist Beta-arrestin activity: Low (linked to reduced respiratory depression) ...