Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...

There is a High Risk of Weather Impact (ROWI) for the NFL's Sunday Night Football matchup between the San Francisco 49ers ...

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The ...

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an ...

San Francisco 49ers star linebacker Fred Warner revealed that he has been playing through a broken bone in his ankle since ...

The 49ers have revealed their latest injury report from Wednesday’s practice before their Sunday Night Football tilt against ...

With only a few weeks left on the college football slate, NFL draft season is beginning to hit its stride. Before the San ...

Bills' QB Josh Allen is the current favorite for MVP. Expectations aren't something I like to make a habit. However, it's ...

San Francisco 49ers running back Christian McCaffrey is three games into his return from injury. The two-time first-team ...

Amid a 5-6 start for the 49ers this season, head coach Kyle Shanahan sent a message to the locker room about being too online ...

Following their bye week, the Bills (9-2) will take on the San Francisco 49ers (5-6) at Highmark Stadium in Week 13. But ...

What to expect from Sunday Night Football's 49ers vs. Bills matchup. This is one of those games that feels like Buffalo's to ...