The San Francisco 49ers are preparing for their Week 13 contest against the Buffalo Bills on Sunday at Highmark Stadium in ...

The San Francisco 49ers didn't have many changes to their Thursday practice participation report. One big difference between ...

Under head coach Kyle Shanahan, the San Francisco 49ers have spent years falling just inches short of the franchise’s sixth ...

The Buffalo Bills are in great shape heading down the stretch of this 2024 NFL regular season. Coming out of their ...

Hello friends. I’m Dr. Getagrip and I’m here to solve whatever are the ills of our home town football team. Nurse! Who’s our ...

This week, Nick Bosa was asked about the 49ers' upcoming opponent, Bills quarterback Josh Allen. Here's what Bosa said. Q: ...

Since returning from an Achilles tendinitis issue, Christian McCaffrey has dominated the San Francisco 49ers' backfield, ...

Detroit opens Thanksgiving weekend against NFC North rival Chicago. Plus, Kansas City and Buffalo can clinch postseason spots ...

San Francisco 49ers left tackle Trent Williams may be at risk of missing his second consecutive game. On Sunday, the ...

Traffic and parking, what's banned and allowed through security, and more things you need to know before Thursday night's ...

Wide receiver Chris Conley, linebacker Curtis Robinson and more San Francisco 49ers players shared what they're most grateful ...

Snow is in the forecast for Buffalo all weekend, with a 46% chance of snow showers on deck for Sunday’s 8:20 p.m. ET kickoff.