Kyle Shanahan pushed back against the negativity and “unrealistic” expectations regarding Christian McCaffrey’s production in ...

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The ...

During a segment of "Good Morning Football", NFL Network's Peter Schrager coins the last Thanksgiving matchup of the day ...

See who's in and who's out for the Week 13 matchup between the Buffalo Bills and San Francisco 49ers on December 1, 2024.

The 49ers have revealed their latest injury report from Wednesday’s practice before their Sunday Night Football tilt against ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

San Francisco 49ers linebacker Fred Warner says he has been playing through a fractured bone in his ankle since Week 4.

San Francisco 49ers star linebacker Fred Warner revealed that he has been playing through a broken bone in his ankle since ...

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in ...

Weather looks set to play a role in the Buffalo Bills' Week 13 matchup with the San Francisco 49ers.

SANTA CLARA, Calif. (AP) — Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he ...

The San Francisco 49ers are 5-6 entering their matchup with the Buffalo Bills on Sunday, and an NFL executive called out ...