Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...

Kyle Shanahan pushed back against the negativity and “unrealistic” expectations regarding Christian McCaffrey’s production in ...

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The ...

See who's in and who's out for the Week 13 matchup between the Buffalo Bills and San Francisco 49ers on December 1, 2024.

Former Buffalo Bills defensive end Leonard Floyd spoke about facing his old team on Sunday night with the San Francisco 49ers ...

The San Francisco 49ers have opened the practice window for linebacker Dre Greenlaw from the Reserve/Physically Unable to ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an ...

Vern Glenn reports on the annual Feast with the Niners Thanksgiving charity event for a select group of fans in need.

San Francisco 49ers head coach Kyle Shanahan confirmed Wednesday that the team discussed the possibility of signing ...

San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there ...

Bills' QB Josh Allen is the current favorite for MVP. Expectations aren't something I like to make a habit. However, it's ...