HCM is a genetic disease, usually caused by mutations in sarcomere proteins such as myosin, actin, tropomyosin, and myosin-binding protein C.

Purpose: Skin prick test (SPT) and the level of serum-specific IgE (sIgE) antibodies to shrimp have low specificity in the diagnosis of shrimp allergy. Measurement of sIgE to tropomyosin is available ...

SHRIMP allergy is becoming an increasingly recognised health concern in Tunisia, driven by changing dietary habits and rising seafood consumption. A new study conducted at the Pasteur Institute of ...

New research from subtropical Spain shows how exposure to common household mites may prime the immune system to react to edible insects, even in people who’ve never tried them. Study: The Allergy ...

This study investigates the role of a key interaction between Tropomyosin (Tpm) and Troponin T (TnT) in the regulation of cardiac muscle contraction, with a particular focus on understanding ...

TPM3 (tropomyosin 3) is an actin‐binding protein in vascular smooth muscle cells, where posttranslational modifications critically regulate its actin affinity, influencing cardiovascular function.

BRANFORD, Conn.--(BUSINESS WIRE)--Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company™, today announced a newly released preprint publication ...

Impact of Clonal Hematopoiesis–Associated Mutations in Phase I Patients Treated for Solid Tumors: An Analysis of the STING Trial Pooled clinical data from 17 pediatric cases (11 soft-tissue sarcomas, ...

School of Food Science and Technology, National Engineering Research Center of Seafood, Dalian Polytechnic University, Dalian 116034, P. R. China Liaoning Engineering Research Center of Special ...

Two common and potentially deadly heart diseases can be caused by mutations in the same gene. Surprisingly, though, these two conditions are each associated with very different clinical symptoms.

First-in-Human Study of OBI-999, a Globo H-Targeting Antibody-Drug Conjugate, in Patients With Advanced Solid Tumors Eighty-five larotrectinib patients and 28 non-TRK-inhibitor SoC patients were ...

Striated muscle contraction is regulated in a calcium-dependent manner through dynamic motions of the tropomyosin/troponin polymer, a multicomponent complex wrapped around actin-containing thin ...