People inherit two copies of each gene—one from each parent—an evolutionary fail-safe to ensure survival even when one of ...

Researchers from the Walter and Eliza Hall Institute (WEHI)in Australia have found a new way to predict a subset of patients ...

A new study in mice explains how even a single faulty copy of the BRCA1 gene can fuel tumor growth. The findings suggest the dominant “two-hit” hypothesis of cancer development may not tell the full ...

Research shows that the breast cancer gene 1 (BRCA1) not only pushes accurate DNA repair to guard against cancer but promotes subsequent activity in tumor suppression. A new study led by The ...

People of Ashkenazi Jewish descent are at higher risk of developing pancreatic cancer because they are more likely than other ...

Medically reviewed by Adam M. Brufsky, MD, PhD The exact cause or causes of triple-negative breast cancer are unknown, but ...

Results of a cohort of patients with various solid tumors with germline or somatic BRCA1 and 2 mutations treated with talazoparib are reported. BRCA1 is involved in both non homologous end joining, ...

A simple blood test could soon predict which ovarian cancer patients will stop responding to their treatment, paving the way ...

Research led by The University of Texas Health Science Center at San Antonio shows that the breast cancer gene 1 (BRCA1) not only pushes accurate DNA repair to guard against cancer but promotes ...

The current US Supreme Court has no fundamental understanding of a range of medical, engineering, technological, or ...