The Substance” blowtorches a single idea for two hours and 20 minutes, and narratively it turns to ashes by minute 40. It’s easier for a movie to become a talking point that way. Film festival buzz, which “The Substance” enjoyed at its Cannes world premiere,

The actress stars alongside Margaret Qualley and Dennis Quaid in Coralie Fargeat’s gleefully grotesque movie about an aging celebrity who takes an experimental drug that gives her a younger self.

The Substance, the new film starring Margaret Qualley and Demi Moore, has set a record for the latter. The body-horror film follows a fading celebrity (played by Moore) who begins to use a black-market drug that creates a younger version of herself (Qualley).