Fantasy football m-starts for Week 15's Thursday Night Football between the San Francisco 49ers and Los Angeles Rams as ...

No team has dealt with more injuries at the running back position this season than the San Francisco 49ers. The Los Angeles ...

Isaac Guerendo was initially uncertain for Thursday night, but the rookie looks like he might give it a go. Here's the latest ...

Niners running back Isaac Guerendo, who is listed as questionable with a sprained foot, insists he "feels good" for ...

The 49ers host the Rams on Thursday Night Football. They’ve been losing running backs left and right, and now we’re awaiting ...

The 49ers are getting desperate at running back after three injuries. Here’s who is next up in Kyle Shanahan’s offense.

Niners running back Isaac Guerendo, who is listed as questionable with a sprained foot, insists he "feels good" for ...

Held at Levi’s Stadium in Santa Clara, California, the NFL Week 15 game between the Los Angeles Rams and the San Francisco ...

According to ESPN's Adam Schefter, San Francisco 49ers rookie running back Isaac Guerendo is expected to suit up for Thursday ...

“49ers rookie RB Isaac Guerendo plans to play Thursday night vs. the Rams despite his sprained foot that has left him being ...

In Week 14, the San Francisco 49ers handily defeated the Chicago Bears 38-13.

A pass-heavy approach for Brock Purdy and the 49ers will be in play on Thursday night when they take on the Rams in a pivotal NFC West clash.