More information: Kim L. de Luca et al, Genome-wide profiling of DNA repair proteins in single cells, Nature Communications (2024). DOI: 10.1038/s41467-024-54159-4 Provided by Hubrecht Institute ...

A team of Australian scientists has identified a group of proteins that could transform approaches to treating cancer and age ...

New research identified a protein called protein disulfide isomerase that helps repair serious DNA damage, providing a target ...

The discovery of the twisting switch resolves a long-standing question about how the DNA repair protein RNF168, which has a tendency to cause uncontrolled signaling, is switched off.

Manipulating DNA repair proteins can significantly influence base editing efficiency and outcomes. Inhibiting uracil N-glycosylase (UNG) and DNA ligase 3 (Lig3) ...

In 1991, the atomic-level structure of the most common of this protein type in human cells was determined: Like a molecular caterpillar, it consisted of two or more segments joined together, each ...