Strasbourg diagnostic criteria of Schnitzler syndrome. A 67-year-old man presented to our department with recurrent pruritic, not painful, urticaria-like lesions on the extremities and the trunk (Fig.

Vaccine immunotherapy targeting interleukin 6 (IL-6) has shown promising results in the treatment of inflammatory osteoarthritis of the knee, according to a phase 1 double-blind controlled study.

Tiziana Life Sciences has pointed to increased Big Pharma interest in the IL-6 pathway as justification for its decision to spin out its own candidate into a separate company. In September, Tiziana ...

Researchers compared the cardiovascular safety of IL-6 inhibitors vs TNF-α inhibitors among patients with rheumatoid arthritis and comorbid type 2 diabetes. Cardiovascular and renal risks were ...

Abstract: Interleukin-6 (IL-6) is a protein biomarker that rises in concentration due to infections, tissue damage, and indicates the severity of sepsis, which is a leading cause of death globally.

Previous studies had indicated that treatments for the rare condition known as VEXAS were either not very effective or came with major side effects. Interleukin-1 inhibitors are among the treatments ...

The last time I spoke about Tourmaline Bio, Inc. (TRML), it was with respect to a Seeking Alpha article entitled "Tourmaline Bio: TRANQUILITY Study Data Lends Credibility For IL-6 Inhibition." With ...

TARGETING IL-6 signaling shows reassuring safety and effectiveness in older patients with rheumatoid arthritis (RA), according to recent postmarketing and registry data. IL-6 plays a central role in ...

Objective Severe dengue in children may present with a hyperinflammatory phenotype resembling cytokine storm or secondary haemophagocytic lymphohistiocytosis, characterised by refractory shock, ...