This will enable the full potential of proteomics to be realised in areas like biomarker discovery, patient stratification and understanding drug mechanisms of action. If you want to find out more ...

This variability in the efficacy of drugs with similar mechanisms of action likely reflects that the efficacy to disrupt the function of proteostasis machinery is dependent on the specific molecular ...

About 32% of people who have had prior damage from lung diseases will die after five years if they also get a common fungal ...

Secondary objectives included assessing the frequency of changes in antifungal therapy due to infusion-related reactions involving amphotericin B formulations, evaluating mycological cure rates in ...

It is a broad-spectrum biocide that has been used for many years in the United States as an antibacterial and antifungal agent. [1] It is currently used in the United States primarily in hand ...

Fluconazole oral tablet is a generic drug prescribed for certain types of fungal infections. Fluconazole has interactions with some other drugs. Examples include glipizide, citalopram, and ...

While the preferred treatments are an oral medication called terbinafine or the use of medicated creams applied to the skin, there's some evidence to support tea tree oil and other natural antifungal ...

Now, its spent some of that budget on a new antifungal from Scynexis that could ... GSK is paying $90 million upfront for rights to the drug, with another $503 million on the table if Brexafemme ...

Drug screening is the process by which potential ... for fundamental research into importin β1-mediated nuclear import mechanisms and a therapeutic lead in human diseases. Generative models ...

Target validation can include: determining the structure-activity-relationship of analogs of the small molecule; generating a drug-resistant ... of cancer cells by a mechanism of targeted RhoGAP ...

Scientists at Weill Cornell Medicine have uncovered a critical mechanism driving the growth of treatment-resistant ... that targeting EZH2’s alternative activities could reverse drug resistance.

The fight against drugs in our nation requires collaboration among stakeholders, the government, communities, and individuals to make a difference in our lives and work toward a drug-free nation.