Researchers at the University of North Carolina at Chapel Hill have uncovered how chronic inflammation disrupts the immune ...
Clonal hematopoiesis (CH), the benign clonal expansion of hematopoietic stem cells, is often caused by somatic sequence variations in genes associated with hematologic malignancies. Over the past ...
In a significant breakthrough for cancer immunotherapy, collaborative studies published simultaneously in Immunity & ...
In a first-in-human study, researchers at The University of Texas MD Anderson Cancer Center observed strong responses and early signs of antitumor activity in patients with difficult-to-treat ...
Muscle stem cells repurpose the tenogenic factor Scx to establish a muscle-specific transcriptional program that sustains stem cell expansion, migration, differentiation, fusion, self-renewal, and ...
There is an emerging convergence between atherosclerotic cardiovascular disease and cancer, driven by shared risk factors and overlapping pathophysiologic mechanisms. Traditional factors, such as ...
A team led by UCL researchers with Great Ormond Street Hospital (GOSH) and Moorfields Eye Hospital, found B cells—alongside T cells—play a key role in arthritis-related eye disease (JIA uveitis), a ...
Dr. Sebastian Scheich of University Hospital Frankfurt will receive around €2 million over the next six years through the ...
Diffuse large B-cell lymphoma (DLBCL) is an aggressive and rapidly progressing form of lymph node cancer that affects around 6,000 people in Germany ...
T cells sit at the center of modern immunotherapy, yet many of the rules that govern their activation, differentiation, dysfunction (e.g., exhaustion), and ...
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