Here we present the crystal structure of MutS in complex with a 30-base pair (bp) DNA oligomer with a G·T mismatch at position 9. The non-conserved 53 amino acids at the carboxy terminus were ...

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

Harnessing the advantages of DNA nanotechnology, TETRIS leverages hybrid molecular structures as smart encoders to map protein interactions directly in patient samples.

Scientists have shed new light on the rhino family tree after recovering a protein sequence from a fossilized tooth from more ...

Chromatin, the mix of DNA and protein that houses each cell's genome, is more resilient to aging than previously thought, suggests a study published in the Journal of the American Chemical Society ...

A scientific team led by Christian Seiser from MedUni Vienna's Center for Anatomy and Cell Biology has now discovered a previously unrecognised control point for the repair of damage to genetic ...

Explore how DNA and RNA differ in structure, function and composition, and why these distinctions are key to genetic storage, expression and protein synthesis.<br /> ...

We are going to push the boundaries of biological design way beyond individual protein molecules to more complex systems involving many proteins, or to proteins bound to RNA or DNA.

DNA is perhaps the most famous molecule on earth. Here we explain what it is, what it does, and how it is crucial for health.

Proteins interact with DNA to regulate many vital processes in cells. Nearly 40 years ago, researchers developed a way to map these molecular connections.

DeepPBS allows scientists and researchers to input the data structure of a protein–DNA complex into an online computational tool.

This is called the Wobble hypothesis. Until now such synonymous changes in DNA were deemed “silent” mutations that did not affect the structure or function of the resulting protein.