Assessing the distribution of a medication in the brain is critical for the treatment of a vast range of neurological ...

Summary: New research reveals how a tiny chemical mark on RNA helps wire the brain during development. Scientists discovered that m6A methylation regulates the production of proteins essential for ...

In a study of human immune cells infected with HIV, the virus that causes AIDS, scientists at Johns Hopkins Medicine say a ...

AlphaGenome scores mutation effects across coding and non-coding DNA, bringing gene insights to the base-pair level.

Remote-controlled microflow using light-controlled state transitions within DNA condensates has been reported by scientists ...

Remote-controlled microflow using light-controlled state transitions within DNA condensates has been reported by scientists from Institute of Science ...

Researchers at The University of Texas at Arlington have developed a new computational tool that helps scientists pinpoint proteins known as transcriptional regulators that control how genes turn on ...

Transcription factor binding sites (TFBSs) are relatively short (5-15 bp) and degenerate. Identifying them is a computationally challenging task. In particular, protein binding microarray (PBM) is a ...

Characterization of non-coding variants associated with transcription-factor binding through ATAC-seq-defined footprint QTLs in liver. The American Journal of Human Genetics , 2025; DOI: 10.1016/j ...

This binding of ERα on stronger EREs was motif driven as they profoundly lost ERα upon mutation in p-box of ERα that perturbs its DNA binding ability (Fig. 3A,B). Contrastingly, the lower strength ERE ...