Researchers working on an incurable blood cancer can now use a new lab model that could make testing potential new treatments and diagnostics easier and quicker, new research has found.

New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain ...

From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body's ...

New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain ...

Chunks of flipped DNA appear to accelerate evolution in fish. This discovery could reshape our understanding of how ...

A recent research finding adds to evidence that brain inflammation is a major driver of neurodegenerative disorders such as ...

To test whether the inversion indeed functions as a balancer chromosome, we crossed the inversion to a recessive lethal mutation, Hoxb4r (ref. 21), which lies in the inversion interval.

However, APP gene linkage and mutations account for only a very small portion of FADs. [2, 3, 4] Another two closely related genes, the presenilins (PSEN1 and PSEN2), located on chromosomes 14q24 ...

The remaining chromosomes were not measured because of their very small size, being considered microchromosomes. Karyotypes were arranged according to chromosome size and centromere position.

A heterozygous pericentric inversion of chromosome 12 (inv (12)) was prenatally diagnosed. The breakpoints were localized to p12.3 and q14, resulting in more than one-third of the total length of ...

Figure 1 - Cytogenetic analysis. A) Metaphase with ring chromosome (1), double minutes (2) and figure (3) (Sample IP028). B) Karyogram showing chromosome 3 inversion (Sample IP037). C) Karyogram ...

PS1 on Chromosome 14q24.3 and PS2 Genes on Chromosome 1q31-q42 Mutations in the PS1 gene are responsible for the most aggressive form of AD and account for 18-50% of all early-onset AD cases. [4] ...